Sports drinks and energy drinks are multi-billion dollar industries. How good are these products? When is water the best hydration fuel and when are sports drinks truly needed to optimize the exercise performance. This all-inclusive lecture will discuss the many physiological mysteries of water in the human body, the need for hydration during exercise, hydration and disease, post-exercise hydration, hydration and mental performance, and answer numerous pertinent questions about hydration, sports drinks and energy drinks.